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The ubiquitin E3 ligase substrate adapter cereblon (CRBN) is a target of thalidomide and lenalidomide 1, therapeutic agents used in the treatment of haematopoietic malignancies 2-4 and as ligands for targeted protein degradation 5-7.These agents are proposed to mimic a naturally occurring degron; however, the structural motif recognized …

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https://themercury.com/features/like-water-shows-another-more-complex-view-of-bruce-lee/article_7aaab04c-96b0-5df6-b99d-79719f08fffd.html7 years following discharge or until patient reaches the age of 21, whichever is longer. Alaska Stat. § 18.20.085(a) (2008). Arizona

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Hard to believe it's 2019 and I'm still getting bitten by this.. If I order french fries and you give me a bowl of chili, claiming that I should have known that you use the words french fries to refer to a bowl of chili is stupid.

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